PROSPERO Registration Services – Streamlining Systematic Review Registration for Researchers

Ensuring Transparency and Credibility in Systematic Reviews

Systematic reviews play a pivotal role in evidence-based medicine (EBM) and healthcare decision-making. PROSPERO (International Prospective Register of Systematic Reviews) is the gold-standard platform for registering systematic review protocols, ensuring transparency, reducing bias, and preventing duplication of research.

At Clievi, we specialize in PROSPERO registration services, assisting researchers, healthcare professionals, and academic institutions in accurately drafting, structuring, and submitting systematic review protocols in compliance with international best practices. Our expertise ensures efficient registration, adherence to PRISMA-P guidelines, and regulatory alignment for a seamless review process.

Our PROSPERO Registration Services

1. Comprehensive Systematic Review Protocol Development

• Defining Research Scope & Objectives – Refining research questions using PICO (Population, Intervention, Comparison, Outcome) and SPIDER (Sample, Phenomenon of Interest, Design, Evaluation, Research type) frameworks.
• Eligibility Criteria Formulation – Clearly defining inclusion and exclusion criteria based on study design, population, interventions, comparators, and outcomes.
• Search Strategy Documentation – Structuring detailed search methodologies across major databases like PubMed, Embase, Cochrane Library, Scopus, Medline, and grey literature sources.
• Data Extraction & Risk of Bias Assessment Plan – Outlining methods for data synthesis, risk-of-bias evaluation using Cochrane RoB 2.0, Newcastle-Ottawa Scale (NOS), and GRADE criteria.

2. PROSPERO Registration & Submission Support

• Step-by-Step Registration Assistance – Completing the PROSPERO online submission process, ensuring adherence to formatting and content requirements.
• PRISMA-P Compliance & Review – Aligning protocol submissions with Preferred Reporting Items for Systematic Review and Meta-Analysis Protocols (PRISMA-P) guidelines for methodological rigor.
• Justification of Study Design – Providing detailed explanations for study methodology, data synthesis techniques, and meta-analysis plans.
• Handling Review & Revisions – Addressing reviewer queries, ensuring successful registration, and making necessary protocol amendments.

3. Post-Registration Updates & Amendments

• Ongoing Protocol Updates – Assisting with protocol modifications in PROSPERO due to changes in search strategies, inclusion criteria, or analysis methodologies.
• Publication-Ready Systematic Review Protocols – Structuring registered protocols for submission to peer-reviewed journals and academic repositories.
• Preprint & Open Access Support – Formatting PROSPERO-registered protocols for preprint servers like MedRxiv and ResearchGate for early dissemination.

Why Choose Clievi for PROSPERO Registration Services?

• Expert-Led Protocol Development – A team of experienced systematic review specialists, evidence synthesis experts, and medical writers ensures the highest quality submissions.
• Compliance with International Standards – Adherence to PRISMA-P, Cochrane Handbook, EQUATOR Network, and other evidence-based research guidelines.
• Efficient & Hassle-Free Submission Process – Streamlined assistance for accurate, prompt, and complete PROSPERO registration.
• Regulatory & Publication-Ready Documentation – Ensuring systematic review protocols meet journal and funding agency requirements.
• Customized Support for Researchers & Institutions – Tailored services for academics, pharmaceutical companies, healthcare organizations, and independent researchers.

Secure Your Systematic Review’s Transparency with Clievi

PROSPERO registration is a crucial step in ensuring credibility, reproducibility, and methodological transparency for systematic reviews. Partner with Clievi for expert-led, precision-driven, and hassle-free PROSPERO registration services that enhance the impact and recognition of your research.

Register your systematic review with PROSPERO today – Get expert guidance from Clievi!